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Taken together, PEA and its congeners could stand for an ground breaking therapeutic strategy from the management of blended neuropathies.Idea of exogenous PEA pharmacokinetics is still at an early stage [212]. Future investigation should really evaluate the specific tissue distribution and site of metabolism of PEA to be able to determine correct

2005). These success weren't surprising if we contemplate that PEA is often a poorly drinking water‐soluble compound, which often can Restrict its oral absorption and bioavailability, However they may additionally suggest a short‐lived action of PEA, in arrangement with the fact that this compound is degraded by two distinct hydrolases, that is